I am focusing on vacation destinations in the mainland USA that are wheelchair-accessible and/or chronic-illness-friendly. I am posting about one East Coast city, one West Coast city, one Mid-West city, and a national park and beach destination. Of course, there are many, many others.

Here are five of my favorite cruise lines that are genuinely committed to welcoming travelers with mobility needs. These are not in any specific order and instead are based on travel style.